Description
Overview of Letrozole
Letrozole is a medication primarily used to treat certain types of breast cancer in postmenopausal women. It is classified as an aromatase inhibitor, which works by decreasing estrogen levels in the body, thereby slowing the growth of hormone-sensitive tumors.
Dosage and Administration
Letrozole is typically prescribed in tablet form, with a common dosage of 2.5 mg taken once daily. However, it can also be available in liquid form, such as 5 mg/mL in a 30 mL bottle.
| Formulation | Dosage | Volume |
|---|---|---|
| Letrozole (liquid) | 5 mg/mL | 30 mL |
| Letrozole (tablet) | 2.5 mg | N/A |
Off-Label Use
In addition to its primary use for breast cancer, letrozole is also used off-label to induce ovulation in women experiencing infertility, particularly those with conditions like polycystic ovary syndrome (PCOS). The recommended starting dose for this purpose is 2.5 mg once daily for 5 days.
Important Considerations
- Prescription Only: Letrozole is available only with a doctor’s prescription.
- Monitoring: Patients using letrozole for fertility should be monitored for ovulation.
- Side Effects: Common side effects may include hot flashes, muscle aches, and headaches.
Letrozole is a well-established treatment option for breast cancer and is increasingly recognized for its role in fertility treatments. Always consult a healthcare provider for personalized medical advice and to discuss potential risks and benefits.





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