Description
Buy CJC-1295 No DAC 2mg
🧬 CJC-1295 No DAC 2mg Lyophilized Peptide (Modified GRF 1-29)
Product Overview
Quality Research Chemicals offers premium-grade CJC-1295 No DAC 2mg in highly stable, lyophilized vial formats synthesized exclusively for in-vitro laboratory experimentation, receptor binding assays, and academic research applications. CJC-1295 No DAC, which is also widely known as Modified GRF (1-29) or Tetrasubstituted GRF (1-29), is a synthetic analog of the naturally occurring growth hormone-releasing hormone (GHRH).
The molecular structure features four strategic amino acid substitutions at positions 2, 8, 15, and 27. These specific modifications structurally fortify the compound against rapid enzymatic cleavage by dipeptidyl peptidase-4. Because this variation lacks the Drug Affinity Complex (DAC), it does not bind to plasma albumin. Consequently, it exhibits a much shorter half-life than its DAC-bound counterpart, providing investigators with an ideal tool for studying acute, pulsatile growth hormone signaling pathways. Every batch is thoroughly analyzed via third-party validation to guarantee maximum chemical identity and structural purity.
🔬 Technical Specifications & Chemical Profile
- Compound Name: CJC-1295 No DAC
- Alternative Names: Modified GRF 1-29, Tetrasubstituted GRF 1-29, Mod GRF 1-29
- Active Concentration: 2mg per vial
- Sequence Structure: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
- Physical Form: Lyophilized (freeze-dried) sterile white crystalline powder
- Purity Level: ≥99% verified via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS)
- Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
- Molecular Weight: 3367.97 g/mol
- Format: Airtight, vacuum-sealed clear glass vials with rubber stoppers and protective aluminum flip-off caps
🧪 Primary Research Applications
CJC-1295 No DAC 2mg vials are manufactured to support advanced multi-disciplinary inquiries across key scientific domains:
- Pulsatile Signaling Dynamics: Investigating acute GHRH receptor binding kinetics and examining subsequent episodic downstream cAMP activation cycles.
- Enzymatic Resistance Profiling: Modeling the protective effects of tetrasubstitution against in-vitro plasma protease breakdown compared to endogenous GHRH.
- Somatotropic Cell Interactions: Studying the cellular mechanisms that govern growth hormone synthesis and transcription inside isolated anterior pituitary cell lines.
- Synergistic Co-Activation: Mapping receptor responses when this GHRH analog is paired with growth hormone secretagogues or GHRP compounds in cellular assays.
📦 Storage, Stability, and Reconstitution Guidelines
To protect the delicate peptide bonds and ensure reproducible experimental data, proper handling protocols must be maintained. The lyophilized powder should be stored at -20°C for standard lab workflows up to 12 months. For long-term compound archives, however, it is highly recommended to preserve the vials at -80°C. Additionally, the compound must be kept completely isolated from moisture, humidity, and direct UV light exposure.
During the reconstitution process, allow the vial to come to room temperature prior to solvent introduction. Reconstitute slowly utilizing sterile bacteriostatic water or sterile saline vector, introducing the liquid gently along the glass sidewall. Do not shake or agitate aggressively, because structural fracturing of the peptide chain may occur. Swirl in a slow, circular motion instead. Once dissolved, aliquot the solution into small, single-test volumes and freeze immediately at -20°C or below to avoid repeated freeze-thaw cycles, which induce immediate molecular decay.
⚠️ Laboratory Safety Disclaimer
THIS PRODUCT IS INTENDED SOLELY AS A LABORATORY RESEARCH CHEMICAL.
CJC-1295 No DAC 2mg distributed by Quality Research Chemicals is strictly intended for in-vitro laboratory testing, analytical modeling, and institutional evaluation. Therefore, this compound is not for human consumption, clinical trial injection, diagnosis, cosmetic treatment, or veterinary use. All handling must be restricted to qualified professional researchers using standard personal protective equipment (PPE).
CJC-1295 No DAC 2mg distributed by Quality Research Chemicals is strictly intended for in-vitro laboratory testing, analytical modeling, and institutional evaluation. Therefore, this compound is not for human consumption, clinical trial injection, diagnosis, cosmetic treatment, or veterinary use. All handling must be restricted to qualified professional researchers using standard personal protective equipment (PPE).
🔒 The Quality Research Chemicals Advantage
- Independent Quality Certification: Third-party HPLC/MS purity analysis profiles available for documentation verification upon request.
- Dosing Integrity: Vacuum-lyophilized packaging guarantees zero ambient moisture absorption and exact concentration accuracy.
- Optimized Supply Chain: Rapid processing and secure domestic shipping protocols maintain the integrity of temperature-sensitive items.
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